Pradaxa bleeding risk appears no worse than warfarin – FDA

(Reuters) – The risk of serious bleeding among new users of Pradaxa, a blood-clot preventer made by Germany’s Boehringer Ingelheim, appeared to be no higher than in patients on the widely used standard blood thinner warfarin, U.S. regulators said.

The announcement Friday by the U.S. Food and Drug Administration may allay some safety concerns about Pradaxa, a pill developed by the privately held drugmaker Boehringer, to prevent strokes among patients with an irregular heartbeat known as atrial fibrillation.

The regulator’s findings were based on an assessment of insurance claims and other data.

Over the past year, the FDA has been analyzing reports of serious bleeding among patients prescribed Pradaxa, including gastrointestinal bleeding and bleeding in the brain.

The agency said on Friday a comparable risk of serious bleeding for Pradaxa and warfarin was suggested by its review of insurance claims and by analyzing electronic healthcare data from multiple other sources.

The FDA said it was also planning other assessments of Pradaxa’s bleeding risks.

The medicine competes with Xarelto, a stroke-prevention pill for atrial fibrillation patients developed by Johnson & Johnson and Bayer AG.

A similar pill being developed by Bristol-Myers Squibb and Pfizer Inc, Eliquis, is awaiting U.S. approval and is deemed by many Wall Street analysts to be the most impressive of a new generation of oral drugs to replace warfarin.

(Reporting by Ransdell Pierson in New York; Editing by Bernadette Baum)

Medications/Drugs News Headlines – Yahoo! News

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Will final jobs report affect the election?

President Barack Obama and Republican rival Mitt Romney on Friday seized on the last jobs report before Election Day to reinforce their political arguments about the economy. Neither side, however, expected that the better-than-expected news would change many minds.

In a statement, Romney said that come Tuesday the choice would be "between stagnation and prosperity."

Obama, meanwhile, in front of a rowdy crowd of cheering supporters at the Franklin County Fairgrounds in Hilliard, Ohio, said, "This morning we learned that companies hired more workers in October than at any time in the last eight months.

"We've made real progress--but we are here today because we know we've got more work to do," Obama continued. "As long as there's a single American who wants a job and can't find one, as long as there are families working harder but falling behind, as long as there's a child anywhere in this country who's languishing in poverty and barred from opportunity, our fight goes on, we've got more work to do."

Neither campaign expected the new figure to do much to change the dynamic of the race. Aides on both sides have said in recent weeks that Americans' views of the economy are essentially fixed by now, barring a dramatic change.

The Labor Department's monthly jobs report did not provide such a tectonic shift. It showed that the economy added more jobs than experts had predicted and bolstered Obama's argument that he has overseen a slow but steady recovery from the 2007-2008 global economic meltdown.

At the same time, Republicans led by Romney seized on the news to charge that the incumbent has failed to bring about sturdier growth. At the current rate, it would take years to return to pre-recession levels. And no incumbent has faced the voters with unemployment this high since Franklin D. Roosevelt.

"On Tuesday, America will make a choice between stagnation and prosperity," Romney also said. "For four years, President Obama has told us that things are getting better and that we're making progress. For too many American families, those words ring hollow. We can do better."

Non-farm payrolls added 171,000 jobs last month, beating forecasts of about 125,000. The Labor Department also revised its previous estimates of employment growth in August and September upward by 84,000 jobs.

The unemployment rate ticked up from 7.8 percent to 7.9 percent, but chiefly as a result of more Americans getting off the sidelines and looking for work (those not looking are not counted in the jobless rate). Democrats emphasized that Obama had inherited a disastrous economy from George W. Bush and reversed what had been accelerating jobs losses. Republicans noted that the unemployment rate when Obama took office was 7.8 percent.

"Today's increase in the unemployment rate is a sad reminder that the economy is at a virtual standstill," Romney added. "The jobless rate is higher than it was when President Obama took office, and there are still 23 million Americans struggling for work."

One of the political challenges for Romney was that unemployment was lower than the national average in some critical battleground states. In September, it was 7 percent in Ohio, and 5.9 percent in Virginia.

An ABC News/Washington Post poll released on Thursday painted a mixed picture of voters' views about the economy. Fifty-four percent of likely voters expressed confidence that the economy would improve under Romney, against 47 percent for Obama. But 51 percent of those surveyed still blamed George W. Bush for the current conditions, against 36 percent for Obama. The Democrat has made tying Romney to Bush a centerpiece of his closing argument.

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Syrian rebels kill 28 soldiers, several executed

BEIRUT (Reuters) – Anti-government rebels killed 28 soldiers on Thursday in attacks on three army checkpoints around Saraqeb, a town on Syria’s main north-south highway, a monitoring group said.

Some of the dead were shot after they had surrendered, according to video footage. Rebels berated them, calling them “Assad’s Dogs”, before firing round after round into their bodies as they lay on the ground.

The highway linking the capital Damascus to the contested city of Aleppo, Syria’s commercial center, has been the scene of heavy fighting since rebels cut the road last month. Saraqeb lies about 40 km (25 miles) south of Aleppo

In other developments, China put forward a new initiative to resolve the 19-month-old conflict, including a phased, region-by-region ceasefire and the setting up of a transitional governing body.

A Chinese Foreign Ministry spokesman said Beijing had made the proposal to international peace envoy Lakhdar Brahimi – whose own call for a truce over the Muslim holiday of Eid was largely ignored by both sides.

The United States meanwhile has called for an overhaul of Syria’s opposition leadership, signaling a break with the largely foreign-based Syrian National Council to bring in more credible figures.

A meeting in Qatar next week of foreign powers backing the rebels will be an opportunity to broaden the coalition against President Bashar al-Assad, U.S. Secretary of State Hillary Clinton said in Zagreb on Wednesday.

The United States and its allies have struggled for months to craft a credible opposition coalition, while Assad has counted on the support of Russia, Iran and, to a lesser extent, China. International efforts to end the violence have all foundered.

More than 32,000 people have been killed since protests against Assad, an Alawite who succeeded his late father Hafez in ruling the mostly Sunni Muslim country, first broke out on city streets. The revolt has since degenerated into full-scale civil war, with the government forces relying heavily on artillery and air strikes to thwart the rebels.

CHECKPOINT ATTACKS

The army has lost swathes of land in Idlib and Aleppo provinces but is fighting to control towns along supply routes to Aleppo city, where its forces are fighting in many districts.

The head of the pro-opposition Syrian Observatory for Human Rights, Rami Abdelrahman, said two of the attacked checkpoints at Saraqeb were on the Damascus-Aleppo highway. The third was near a road linking Aleppo with Latakia, a port city still mostly controlled Assad’s forces.

“The rebels will not stay at the checkpoints for long as Syrian warplanes normally bomb positions after rebels move in,” Abdelrahman said.

Five rebels died in the fighting and at least 20 soldiers were killed at the third site, including those shot after surrendering, he said.

The video footage showed a group of petrified men, some bleeding, lying on the ground as rebels walked around, kicking and stamping on their captives.

One of the captured men says: “I swear I didn’t shoot anyone” to which a rebel responds: “Shut up you animal … Gather them for me.” Then the men are shot dead.

Reuters could not independently verify the footage.

The Observatory said the al Qaeda-inspired Jabhat al-Nusra rebel group was responsible for the executions.

Islamist rebel units are growing in prominence in the war – a cause for concern for international powers as they weigh up what kind of support to give the opposition.

U.S. President Barack Obama’s administration has said it is not providing arms to internal opponents of Assad and is limiting its aid to non-lethal humanitarian assistance. It concedes, however, that some of its allies are providing lethal assistance.

Russia and China have blocked three U.N. Security Council resolutions aimed at increasing pressure on the Assad government, leading the United States and its allies to say they could move beyond U.N. structures for their next steps.

China has been strongly criticized by some Arab countries for failing to take a stronger stance on the conflict. Beijing has urged the Assad government to talk to the opposition and take steps to meet demands for political change.

“More and more countries have come to realize that a military option offers no way out, and a political settlement has become an increasingly shared aspiration,” Chinese Foreign Ministry spokesman Hong Lei said in Beijing.

He said China’s new proposal was aimed at building international consensus and supporting peace envoy Brahimi’s mediation efforts.

(Additional reporting by Ayat Basma, Laila Bassam and Dominic Evans in Beirut and Terril Yue Jones in Beijing; Writing by Oliver Holmes; Editing by Angus MacSwan)

World News Headlines – Yahoo! News

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Suicide Silence singer Lucker dies in California motorcycle accident

LOS ANGELES (Reuters) – Mitch Lucker, the lead singer of extreme heavy metal band Suicide Silence, died on Thursday of injuries suffered in a motorcycle accident in Huntington Beach, California, police said.

The band from Southern California was given the Golden Gods award for best new talent by Revolver magazine in 2009.

Lucker, 28, was on a new Harley Davidson motorcycle driving in the Orange County city of Huntington Beach on Halloween night when he lost control and crashed into a light pole, according to a statement from the local police department.

He was taken to the University of California, Irvine Medical Center where he later died, police said. Investigators said they were looking into the cause of the collision and whether alcohol was a factor.

“There’s no easy way to say this,” the band said in a post on Facebook. “Mitch passed away earlier this morning from injuries sustained during a motorcycle accident.”

Suicide Silence in 2007 came out with the album “The Cleansing” and followed that up with the 2009 “No Time to Bleed” and last year’s “The Black Crown,” which made its way to No. 9 on the Billboard hard rock chart.

The band, whose musical style is referred to as “deathcore,” is originally from Riverside, California, a working-class community 50 miles east of Los Angeles.

(Reporting by Alex Dobuzinskis; Editing by Cynthia Johnston and Will Dunham)

Music News Headlines – Yahoo! News

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Court in UK tells Apple to change statement on Samsung case

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Judge backs Catholic firm over contraception mandate

(Reuters) – A Catholic-owned family business in Michigan does not have to comply with the provision of the new U.S. healthcare law that requires private employers to provide employees with health insurance that covers birth control, a federal judge in Detroit has ruled.

U.S. District Judge Robert Cleland, in a ruling late Wednesday, temporarily blocked the government from forcing the owner of Weingartz Supply Company, which sells outdoor power equipment, to include contraception in its health coverage of employees.

The ruling only affects the company’s Catholic proprietor, Daniel Weingartz, and the approximately 170 people who work for him. But it opens the door for other firms to seek relief on religious grounds.

Cleland is now the second federal judge to temporarily block part of the Affordable Care Act of 2010 from being enforced against the religious owners of a family business. In July, U.S. District Judge John Kane in Denver temporarily prevented the government from requiring the Catholic owners of Hercules Industries Inc, a private manufacturer of heating, ventilation and air conditioning equipment, to provide health insurance that covers birth control.

Weingartz was joined in his lawsuit, filed in May, by Legatus, a national association of Catholic business owners.

Roman Catholic bishops and many Republican lawmakers have opposed the birth control provision, and priests have been speaking out against the law from pulpits across the country. Church doctrine opposes artificial contraception but most American Catholics do not adhere to church policy.

Lawyers for the Department of Health and Human Services argued that granting exceptions for small business owners would interfere with the government’s ability to implement the law. The contraception mandate serves the government’s interests in promoting public health and gender equality, they argued.

The federal government has carved out an exemption from the contraception requirement for religious organizations. Allowing additional relief for Weingartz Supply Co and its 170 employees would not be a much greater burden, the company argued. Cleland agreed with Weingartz.

“The harm in delaying the implementation of a statute that may later be deemed constitutional must yield to the risk presented here of substantially infringing the sincere exercise of religious beliefs,” Cleland wrote in a 29-page opinion.

The judge refused to shield Legatus from the law, finding that the non-profit association would likely qualify for the government’s accommodation for religious organizations. If the government later tries to enforce the mandate against Legatus, the group can resume its court challenge then, Cleland wrote.

Erin Mersino, an attorney with the Thomas More Law Center, which filed the challenge, called the ruling “not only a victory for our clients, but for religious freedom.”

The Department of Health and Human Services did not immediately respond to a request for comment.

More than 20 lawsuits have been filed against the birth control mandate by organizations including the University of Notre Dame, Catholic University of America and the Archdiocese of New York.

In July, another federal judge in Nebraska dismissed a similar lawsuit brought by seven states, two Catholic individuals and three Catholic non-profit institutions, finding that the plaintiffs did not face any immediate harm from the law.

The case in U.S. District Court for the Eastern District of Michigan is Legatus et al v. Sebelius et al, No. 12-12061.

(Reporting By Terry Baynes in New York; Editing by Claudia Parsons)

Sexual Health News Headlines – Yahoo! News

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'A mess everywhere': East Coast struggles to recover

(Reuters) - Rescuers searched flooded streets and swamped houses for survivors, drivers lined up for hours to get scarce gasoline and millions remained without power on Thursday as New York City and nearby coastal towns struggled to recover from one of the biggest storms ever to hit the United States.

New Yorkers heard the rumble of subway trains for the first time in four days as limited service resumed, but the lower half of Manhattan still lacked power and surrounding areas including Staten Island, the New Jersey shore and the city of Hoboken remained crippled from a record storm surge and flooding.

At least 87 people died in the "superstorm" that ravaged the northeastern United States on Monday night. Officials said the number could climb as rescuers searched house-to-house through coastal towns.

The hunt for gasoline added to a climate of uncertainty as the death toll and price tag of the storm rose.

"I'm so stressed out," said Jessica Bajno, 29, a school teacher from Elmont, Long Island, who was waiting in line for gas. "I've been driving around to nearby towns all morning, and being careful about not running out of gas in the process. Everything is closed. I'm feeling anxious."

More deaths were recorded overnight in the New York City borough of Staten Island, where authorities recovered 17 bodies after the storm lifted whole houses off their foundations. Among the dead were two boys, aged 4 and 2, who were swept from their mother's arms by the floodwaters, police said.

In all, 38 people died in New York City, officials said.

The financial cost of the storm also promised to be staggering. Disaster modeling company Eqecat estimates Sandy caused up to $20 billion in insured losses and $50 billion in economic losses, double its previous forecast.

At the high end of the range, Sandy would rank as the fourth-costliest catastrophe ever in the United States, according to the Insurance Information Institute, behind Hurricane Katrina in 2005, the September 11 attacks of 2001, and Hurricane Andrew in 1992.

JERSEY SHORE STAGGERS

In hard-hit New Jersey, where oceanside towns saw entire neighborhoods swallowed by seawater and the Atlantic City boardwalk was destroyed, the death toll doubled to 12.

Floodwaters finally receded from the streets of Hoboken, just across the Hudson River from Manhattan, leaving behind a stinky mess of submerged basements and displaced cars littering the sidewalks.

"The water was rushing in. It was like a river coming," said Benedicte Lenoble, a photo researcher from Hoboken. "Now it's a mess everywhere. There's no power. The stores aren't open. Recovery? I don't know."

In neighboring Jersey City, drivers negotiated intersections without traffic lights. Shops were shuttered and lines formed outside pharmacies while people piled sodden mattresses and furniture along the streets. The city imposed a curfew and banned driving from 7 p.m. to 7 a.m.

New Jersey favorite son Bruce Springsteen, along with Jon Bon Jovi and Sting, will headline a benefit concert for storm victims Friday night on NBC television, the network announced.

The U.S. government agreed to cover 100 percent of emergency power and public transportation costs through November 9 in eight New Jersey counties. The Federal Emergency Management Agency, which already pledged aid directly to victims and local governments, told New Jersey's U.S. senators of the decision, an aide to Senator Frank Lautenberg said.

Sandy started as a late-season hurricane in the Caribbean, where it killed 69 people, before smashing ashore in the United States with 80 mph winds. It stretched from the Carolinas to Connecticut and was the largest storm by area to hit the United States in decades.

About 4.6 million homes and businesses in 15 U.S. states were without power on Thursday, down from a record high of nearly 8.5 million.

Sandy made landfall in New Jersey with a full moon around high tide, creating a record storm surge that flooded lower Manhattan. By Thursday, the storm had dissipated over the North American mainland.

OBAMA BACK ON CAMPAIGN

After a four-day suspension to deal with the storm, President Barack Obama returned to the campaign trail. Polls show him locked in a virtual tie with Republican challenger Mitt Romney before Tuesday's presidential election.

The president toured devastated New Jersey areas on Wednesday with the state's Republican governor, Chris Christie, a vocal Romney supporter who nonetheless strongly praised Obama's response to the disaster.

Obama received an update on storm recovery efforts Thursday from his crisis management team, White House spokesman Jay Carney told reporters on Air Force One.

More than 36,000 disaster survivors from New York, New Jersey and Connecticut have applied for federal disaster assistance and more than $3.4 million in direct assistance has already been approved, Carney said.

GASOLINE SCARCE

Fuel supplies into New York and New Jersey were being choked off in several ways. Two refineries that make up a quarter of the region's refining capacity were still idle due to power outages or flooding. The New York Harbor waterway that imports a fifth of the area's fuel was still closed to traffic, and major import terminals were damaged and powerless.

In addition, the main oil pipeline from the Gulf Coast, which pumps 15 percent of the East Coast's fuel, remained shut.

The scarcity of fuel, electricity and supplies made cleanup more daunting for barrier towns such as Seaside Heights, part of the Jersey Shore.

Seaside Heights residents who obeyed the mandatory evacuation order were cut off from their homes. The entire community was submerged by the storm surge that washed over the island and into the bay that separates it from the mainland.

"The bay met the ocean," said Frank Meszaros, 43, standing next to the closed bridge that kept him from returning home.

Chris Delman, 30, saw a photograph of his house in a local newspaper Wednesday, noticing it was still standing.

"We ain't living in Seaside no more, that's obvious," Delman said. "I just want to know what I have left."

(Additional reporting by Reuters bureaus throughout the U.S. Northeast; Writing by Daniel Trotta; Editing by Doina Chiacu)

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Mexico’s Day of Dead brings memories of missing

MEXICO CITY (AP) — Maria Elena Salazar refuses to set out plates of her missing son’s favorite foods or orange flowers as offerings for the deceased on Mexico‘s Day of the Dead, even though she hasn’t seen him in three-and-a-half years.

The 50-year-old former teacher is convinced that Hugo Gonzalez Salazar, a university graduate in marketing who worked for a telephone company, is still alive and being forced to work for a drug cartel because of his skills.

“The government, the authorities, they know it, that the gangs took them away to use as forced labor,” said Salazar of her then 24-year-old son, who disappeared in the northern city of Torreon in July 2009.

The Day of the Dead — when Mexicans traditionally visit the graves of dead relatives and leave offerings of flowers, food and candy skulls — is a difficult time for the families of the thousands of Mexicans who have disappeared amid a wave of drug-fueled violence.

With what activists call a mix of denial, hope and desperation, they refuse to dedicate altars on the Nov. 1-2 holiday to people often missing for years. They won’t accept any but the most certain proof of death, and sometimes reject even that.

Numbers vary on just how many people have disappeared in recent years. Mexico’s National Human Rights Commission says 24,000 people have been reported missing between 2000 and mid-2012, and that nearly 16,000 bodies remain unidentified.

But one thing is clear: just as there are households without Day of the Dead altars, there are thousands of graves of the unidentified dead scattered across the country, with no one to remember them.

An investigation conducted by the newspaper Milenio this week, involving hundreds of information requests to state and municipal governments, indicates that 24,102 unidentified bodies were buried in paupers’ or common graves in Mexican cemeteries since 2006. The number is almost certainly incomplete, since some local governments refused to provide figures, Milenio reported.

And while the number of unidentified dead probably includes some indigents, Central American migrants or dead unrelated to the drug war, it is clear that cities worst hit by the drug conflict also usually showed a corresponding bulge in the number of unidentified cadavers. For example, Mexico City, which has been relatively unscathed by drug violence, listed about one-third as many unidentified burials as the city of Veracruz, despite the fact that Mexico City’s population is about 15 times larger.

Consuelo Morales , who works with dozens of families of disappeared in the northern city of Monterrey, said that “holidays like this, that are family affairs and are very close to our culture, stir a lot of things up” for the families. But many refuse to accept the deaths of their loved ones, sometimes even after DNA testing confirms a match with a cadaver.

“They’ll say to you, ‘I’m not going to put up an altar, because they’re not dead,” Martinez noted. “Their thinking is that ‘until they prove to me that my child is dead, he is alive.”

Martinez says one family she works with at the Citizens in Support of Human Rights center had refused to accept their son was dead, even after three rounds of DNA testing and the exhumation of the remains.

“It was their son, he was very young, and he had been burned alive,” Martinez said by way of explanation.

The refusal to accept what appears inevitable may be a matter of desperation. Martinez said some families in Monterrey also believe their missing relatives are being held as virtual slaves for the cartels, even though federal prosecutors say they have never uncovered any kind of drug cartel forced-labor camp, in the six years since Mexico launched an offensive against the cartels.

But many people like Salazar believe it must be true. “Organized crime is a business, but it can’t advertise for employees openly, so it has to take them by force,” Salazar said.

While she refuses to erect an altar-like offering for her son, she does perform other rituals that mirror the Day of the Dead customs, like the one that involves scattering a trail of flower petals to the doorsteps of houses to guide spirits of the departed back home once a year.

Salazar and her family still live in the same home in Torreon, though they’d like to move, in the hopes that Hugo will return there. They pray three times a day for God to guide him home.

“We live in the same place, and we try to do the same things we used to,” said Salazar, “because he is going to come back to his place, his home, and we have to be waiting for him.”

Mistrust of officials has risen to such a point that some families may never get an answer they’ll accept.

The problem is that, with forensics procedures often sadly lacking in Mexican police forces, the dead my never be connected with the living, which is the whole point of the Mexican traditions.

“As long as the authorities don’t prove the opposite, for us they’re still alive,” Salazar said. “Let them prove it, but let us have some certainty, not just the authorities saying ‘here he is.’ We don’t the government to just give us bodies that aren’t theirs, and that has happened.”

Latin America News Headlines – Yahoo! News

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NBC to hold a benefit concert for Sandy victims

NEW YORK (AP) — NBC will hold a benefit concert Friday for victims of Hurricane Sandy featuring some artists native to the areas hardest hit.

Bruce Springsteen and Jon Bon Jovi of New Jersey and Billy Joel of Long Island are scheduled to appear at the concert, hosted by “Today” show co-host Matt Lauer.

Other performers include Christina Aguilera, Sting and Jimmy Fallon.

The telecast will benefit the American Red Cross and will be shown on NBC and its cable stations including Bravo, CNBC, USA, MSNBC and E! Other networks are invited to join in.

“Hurricane Sandy: Coming Together” will air at 8 p.m. EDT and will be taped-delayed in the West.

The telethon will be broadcast from NBC facilities in Rockefeller Center in New York City.

___

NBC is controlled by Comcast Corp.

Entertainment News Headlines – Yahoo! News

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Facebook shares fall as lock-up period expires

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