Sanofi considered moving headquarters abroad: report

























PARIS (Reuters) – Sanofi‘s management considered moving its headquarters abroad in the last few months but the plan was nixed by the drugmaker’s chairman, French weekly Le Journal du Dimanche reported on Sunday, citing sources close to the board.


First mooted in July, when the Socialist government was preparing to introduce a 75 percent tax on top earnings, the plan envisaged moving the headquarters to London or the United States, or at least relocating Chief Executive Chris Viehbacher and his closest associates abroad.





















However, Chairman Serge Weinberg vetoed the project, the newspaper said, saying that Viehbacher had not raised the issue with him.


A Sanofi spokesman denied such plans were discussed and said the company’s recent move to new corporate headquarters in Paris showed its commitment to its base in the city.


Several of the company’s top executives are foreign and spend most of their time travelling abroad.


In addition to German-Canadian Viehbacher, they include Elias Zerhouni, an Algerian-born American in charge of research and development, and Hanspeter Spek, the German-born president of global operations.


Italian Roberto Pucci, senior vice president of human resources, and Karen Linehan, Sanofi’s American-born general counsel, are also part of the executive committee.


Sanofi, which is reshuffling its French research operations at a cost of around 900 jobs, would not be the first French firm to consider moving top executives overseas.


French industrial conglomerate Schneider Electric has kept its headquarters near Paris, but its top managers, including Chief Executive Jean-Pascal Tricoire, relocated to Hong Kong last year in a move to be closer to fast-growing markets in Asia.


Industry Minister Arnaud Montebourg, who has opposed the reorganization of Sanofi’s research activities in France, was cited by the newspaper as saying he hoped the plan was just a rumor.


(Reporting by Elena Berton; Editing by Hugh Lawson)


Health News Headlines – Yahoo! News



Read More..

Forget war on women: Men’s vote could decide who wins the White House


A man ponders his vote in Las Vegas. (David Becker/Getty)


A barrage of attention from the presidential candidates and the news media has been paid to "waitress moms," "Walmart women" and other exhibits of the female species this election, with pundits wondering whether the female gender gap, which works in the president's favor, will carry him over the top on Election Day.


But the focus might be better spent on men.


"The issue is not the women's vote, but the men's vote," Frank Newport, Gallup's editor-in-chief, told Yahoo News. The reason: polls show male voters look much more likely to break from their 2008 voting patterns. If that happens, the men's vote could decide whether Barack Obama or Mitt Romney becomes the next president.


Four years ago, Obama won 49 percent of the male vote, buoyed by historic gains with white men, who chose the Democratic candidate in the highest proportions seen since Jimmy Carter. Even so, most white men—57 percent of them—still voted for John McCain, and a majority of such voters have not backed a Democratic candidate since 1964, when men began abandoning the Democratic party.


This year, Obama's inroads with white men have eroded. Worse, the candidate tracks in the low 40s among all men, not just white ones, in the latest ABC/Washington Post polls. It's possible the president will have lost up to 9 points of ground among male voters compared to 2008. No Democratic candidate has been elected in the past 50 years without gaining close to half of the male vote.


Why are some men abandoning Obama? It's open to interpretation, but one fairly straightforward theory from Newport is that male voters rate Romney higher on the issues that they say are most important:  jobs, the economy and the deficit.


Another theory, laid out in a study by Texas A&M political science professor Paul Kellstedt, is that over the past 30 years men have been more likely to shift rightward during economic downturns, supporting conservative candidates who vow to cut back on government spending. Women also shift rightward in response to a faltering economy, but they are more likely than men to support social safety net programs, and thus much less likely to support a candidate who wants government cuts.


On average, men and women think about the role of government in a fundamentally different way, notes the Democratic pollster Celinda Lake. That difference accounts for one of the biggest shifts in party identification in the past 50 years.


Beginning in 1964, but intensifying with Ronald Reagan's first presidential election, men began leaving the Democratic party and voting Republican. The major causes of the shift were attitudes on both government spending and war, according to the Rutgers political scientist Susan Carroll. For the most part women, who in surveys are not only consistently much more wary of government cutbacks than men, but also much less likely to support foreign military interventions and wars, stayed with the Democrats.


It was men, not women, who changed the political landscape by changing their votes, and women who have been the political stalwarts.


It still makes sense, however, for Romney and Obama to make overt appeals to women. (And to give them fervent shout-outs during debates and party conventions.) According to Lake, women make up about 60 percent of undecided voters this election, which is higher than their projected share of the electorate, 52 percent. And in past elections' exit polls, more women than men said they made up their minds about whom to vote for in the last week before an election.


Still, according to the ABC News/Washington Post pollster Gary Langer and other experts, female voters are not expected to change their votes, on average, significantly from 2008, when they were seven percentage points more likely than men to vote for Obama. This is despite a few recent polls suggesting Romney may be closing in on Obama's support with women. (The Obama campaign has been quick to dismiss these polls.)


"I think it's going to end up in that ballpark. I don't expect it will look vastly different," Carroll said of the gender gap.


Read More..

Brazil’s ‘pop-star priest’ gets mammoth new stage

























SAO PAULO (AP) — Brazil‘s “pop-star priest” is already packing in the crowds at the newly opened mammoth sanctuary that he built for his campaign to stem the exodus of faithful from the Roman Catholic Church in Latin America’s biggest nation.


Brazil still has more Catholics than any other country in the world, with about 65 percent of its 192 million people identifying themselves that way in the 2010 census. But that is down from 74 percent in 2000 and is the lowest since records began tracking religion 140 years ago.





















That’s where Father Marcelo Rossi‘s Mother of God sanctuary comes in. The not-yet-finished structure will seat 6,000 people and have standing room for 14,000 more, church leaders say. In addition, the grounds outside can hold 80,000 people who could watch Mass on outdoor video screens.


After the inaugural Mass on Friday attracted upward of 50,000 people, a beaming Rossi told reporters: “They couldn’t all fit in. There was a crowd that had to stand outside! That’s a sign we’re on the right path, and it’s this sanctuary.”


Similar numbers jammed into the huge church Saturday.


It’s a fitting stage for Rossi, a Latin Grammy-nominated singer who is known for tossing buckets of holy water on worshippers and performing rollicking Christian songs backed by a blasting live band during Mass.


The church sits on 323,000 square feet (30,000 square meters) of land. Church officials declined to confirm how big the actual building is, though local reports put it at 91,500 square feet (8,500 square meters). That would make it one of the world’s 10 biggest churches. A cross soaring 138 feet (42 meters) into the air is the focal point.


The Mother of God sanctuary is anything but traditional. Designed by noted Brazilian architect Ruy Ohtake, it has a wide-open layout giving it the feel of a warehouse. Concrete walls hold up a sloping blue roof that from the outside looks more like a basketball arena than a house of worship. With the church several years away from completion, white plastic chairs were in the place of pews for a lucky few thousand to grab a seat. The rest had to stand.


Rossi dismisses the idea his huge church is a response to the explosion of the evangelical Christian faith in Brazil. Rather, the priest seems to be battling what recent studies indicate is Catholicism’s biggest enemy: indifference.


While millions of Brazilian Catholics joined Pentecostal congregations in the 1990s, a study conducted last year by Brazil’s Getulio Vargas Foundation based on census data found that the Catholics leaving the church these days are mostly becoming nonreligious. Experts have said the trend of Brazilians deciding organized religion isn’t for them poses a more potent threat to Catholic leaders than losses to the Pentecostals.


Rossi chose to open his new church on the Brazilian holiday of Finados, the nation’s version of the Day of the Dead. “A day, a day that was dead, was transformed!” the priest told worshippers during the service, using his gold-plated microphone.


The “pop-star priest” is seen by Brazilian Catholicism as its biggest weapon against the lack of interest, and his new sanctuary adds to his tools of best-selling books and music recordings to keep worshippers interested in what many complain has become a staid institution.


There was nothing stale about his Mass on Friday.


Singing as loud as they could, waving white hankies and swaying with a rocking band, the 20,000 people who jammed into the Mother of God sanctuary hammed it up for TV cameras and shed tears down their cheeks as their superstar priest waved to them from the pulpit. An estimated 30,000 other people had gathered outside, where young boys climbed up into nearby trees trying to get a glimpse of the church grounds as they squinted over a sea of heads streaming out of the sanctuary.


“We have problems, everyone has problems,” worshipper Zuleima de Oliveira Sales said as she stood in the tightly packed sea of people under the soaring blue roof of the structure, her voice choking. “They don’t come to an end, but I have faith, I have faith in Our Lady.”


That’s the sort of belief the Catholic Church is counting on in Brazil and other developing nations. Leaders from the Vatican on down are looking to them as bulwarks against losses in Europe and the U.S., where sex abuse scandals have inspired many people to leave the church. About half of the world’s Catholics live in Latin America.


Pentecostalism was once seen as a major threat to Brazil’s Catholic Church. Pentecostal churches, many of them founded by U.S. evangelicals, saw their membership double to more than 12 percent of the country’s population over the 1990s, with about half of the congregants estimated to be former Catholics.


During the 1990s, Brazil’s economy suffered from hyperinflation and other woes, and Pentecostal churches aggressively recruited in the slums and poor outskirts of Brazil’s cities by offering nuts-and-bolts self-improvement advice as well as Christian ministry.


Since 2003, however, Pentecostal churches have seen growth slow. The percentage of Brazilians calling themselves Pentecostals edged up from 12.5 percent of the population to 13.3 percent.


Yet the Catholic Church has continued to lose parishioners, and church leaders have had little success so far in halting that trend.


Brazil was the first nation outside Europe that Pope Benedict XVI visited, during a five-day tour in 2007 largely aimed at stopping losses in Latin America. During the trip, the pope canonized Brazil’s first native-born saint.


Then Benedict announced last August during the church’s World Youth Day, which drew 1.5 million people to Spain, that the next version of the gathering would be held in Rio de Janeiro in 2013. The pope is expected to attend.


For now, Rossi hopes his big church will bring together tens of thousands of faithful for every Mass, giving new energy to the Catholic faith.


“People want big spaces. They want grand places for prayer,” he told the Globo TV network. “One candle illuminates, 10 candles illuminate — and 100,000 candles light up so much more.”


Latin America News Headlines – Yahoo! News



Read More..

Foxx, Wonder among stars honoring Eddie Murphy

























LOS ANGELES (AP) — However riotous the Eddie Murphy stories from Arsenio Hall, Tracy Morgan, Adam Sandler and Russell Brand, the highlight of Spike TV‘s tribute to Eddie Murphy was the comedian’s duet with Stevie Wonder.


Murphy joined the subject of one of his most classic impressions for a rousing rendition of Wonder’s 1973 hit “Higher Ground” during the taping of the Spike TV special “Eddie Murphy: One Night Only,” which is set to air Nov. 14. The Roots served as the house band.





















Jamie Foxx, Tyler Perry, Martin Lawrence, Chris Rock and Keenan Ivory Wayans were also among those paying tribute to Murphy Saturday at the Saban Theater.


Accompanied by a pretty blonde, Murphy beamed throughout the two-hour program Saturday, saying he was touched by the tribute.


“I am a very, very bitter man,” he said with a beguiling smile. “I don’t get touched easily, and I am really touched.”


Morgan called Murphy “my comic hero” and came onstage wearing a replica of Murphy’s red leather suit from his standup show “Delirious.”


“He set the tone for the whole industry a long time ago,” Morgan said before Saturday’s tribute. “He inspired me in a fearless way.”


Sandler said he was still in high school when he first saw “Delirious,” which he described as “one of the most legendary standup specials of all time.”


“Everybody on the planet wanted to be Eddie,” he said. “He funnier than us. He’s cooler than any of us.”


Samuel L. Jackson said Murphy “changed the course of American film history” by giving Jackson his first speaking role on the big screen, in 1988′s “Coming to America.”


“If it weren’t for Eddie, we might not have all the wonderful films that I’ve made,” Jackson said.


“He is a true movie star,” Jackson continued, lauding Murphy’s performance in “48 Hours” and “Beverly Hills Cop.” ”You became an inspiration for all young African-American actors.”


The program featured clips of Murphy’s standup shows, his film appearances in “Shrek” and “Nutty Professor” and his work on “Saturday Night Live.”


Murphy insisted before the tribute that he is retired.


“I’m just a retired old song and dance man,” he said, adding that he only makes rare appearances these days. “That’s what you do when you’re retired: You come out every now and then and talk about the old days.”


The 51-year-old entertainer took the stage at the conclusion of the tribute to say that he was moved by the honor.


“This is really a touching moving thing, and I really appreciate it,” he said. “You know what it’s like when you have something like this? You know when they sing happy birthday to you? It’s like that for, like, two hours… and I am Eddied out.”


___


Follow AP Entertainment Writer Sandy Cohen on Twitter at www.twitter.com/APSandy.


Entertainment News Headlines – Yahoo! News



Read More..

Google's Android software in 3 out of 4 smartphones

'},"otherParams":{"t_e":1,".intl":"US"},"events":{"fetch":{lv:2,"sp":"1197280665","ps":"LREC,MON","npv":true,"bg":"#FFFFFF","em":escape('{"site-attribute":"_id=\'048ccb9d-45dd-354e-b2f5-74c9b098ca33\' sensitivity=\'0\' rs=\'lmsid:a0770000002GZ5iAAG\' ctype=\'fn_news;News\' ctopid=\'1499989;1550500;2299500;1507989;1506989;1542500;1550000;1507489\' can_suppress_ugc=\'1\' content=\'no_expandable;ajax_cert_expandable;\' ADSSA"}'),"em_orig":escape('{"site-attribute":"_id=\'048ccb9d-45dd-354e-b2f5-74c9b098ca33\' sensitivity=\'0\' rs=\'lmsid:a0770000002GZ5iAAG\' ctype=\'fn_news;News\' ctopid=\'1499989;1550500;2299500;1507989;1506989;1542500;1550000;1507489\' can_suppress_ugc=\'1\' content=\'no_expandable;ajax_cert_expandable;\' ADSSA"}')}}};var _createNodes=function(){var nIds=_conf.nodeIds;for(var i in nIds){var nId=nIds[i];var dId=_conf.destinationMap[nIds[i].replace("yom-","")];n=Y.one("#"+nId);if(n)var center=n.one("center");var node=Y.one("#"+dId);var nodeHTML;if(center && !node){nodeHTML=_conf.nodes[nId];center.insert(nodeHTML);};};};var _prepareNodes=function(){var nIds=_conf.nodeIds;for(var i in nIds){var nId=nIds[i];var dId=_conf.destinationMap[nIds[i].replace("yom-ad-","")];n=Y.one("#"+nId);if(n)var center=n.one("center");var node=Y.one("#"+dId);if(center && node){center.set("innerHTML","");center.insert(node);node.setStyle("display","block");};};};var _darla;var _config=function(){if(YAHOO.ads.darla){_darla = YAHOO.ads.darla;_createNodes();};};var _fetch=function(spaceid,adssa,ps){
if (typeof(ps)!='undefined')
_conf.events.fetch.ps = ps;if(typeof spaceid != "undefined") _conf.events.fetch.sp=spaceid;adssa = (typeof adssa != "undefined" && adssa != null) ? escape(adssa.replace(/\"/g, "'")) : "";_conf.events.fetch.em=_conf.events.fetch.em_orig.replace("ADSSA", adssa);if(_darla){_prepareNodes();_darla.setConfig(_conf);_darla.event("fetch");};};Y.on("domready", function(){_config();});;var that={"fetch":_fetch,"getNodes":_conf.nodes,"getConf":_conf};return that;}();/* Backwards compatibility - Assigning the latest instance to the main fetch function */YUI.PhotoAdsDarla.fetch=YUI.PhotoAdsDarla.photoslightboxdarla.fetch;
});
Y.later(10, this, function() {YAHOO.namespace('Media.Social').Lightbox = {};
});
Y.later(10, this, function() {Y.Media.Article.init();
});
Y.later(10, this, function() {new Y.Media.AuthorBadge();
});
Y.later(10, this, function() {new Y.Media.Branding();
});
Y.later(10, this, function() {Y.on("load", function () {
YUI.namespace("Media.SocialButtons");

var instances = YUI.Media.SocialButtons.instances || [],
globalConf = YAHOO.Media.SocialButtons.conf || {},
vplContainers = [];

Y.all(".ymsb").each(function (node) {
var id = node.get("id"),
conf = YAHOO.Media.SocialButtons.configs[id],
instance;

if (conf) {
instance = new Y.SocialButtons({
srcNode: node,
config: Y.merge(globalConf, conf.config || {}),
contentMetadata: conf.content || {},
tracking: conf.tracking || {}
});
vplContainers.push(
{
selector: "#" + id,
callback: function(node) { instance.render(); instance = conf = id = null; }
});

if (conf.config && conf.config.dynamic) {
instances.push(instance);
}
}
});

Y.Global.Media.ViewportLoader.addContainers(vplContainers);
YUI.Media.SocialButtons.instances = instances;
});
});
Y.later(10, this, function() {if (!Y.Media) {

return;

}

Y.Media.boba_lightbox_module_targets = Y.Media.boba_lightbox_module_targets || {};

Y.Media.boba_lightbox_module_configs = Y.Media.boba_lightbox_module_configs || {};

Y.Media.boba_lightbox_module_dataset = Y.Media.boba_lightbox_module_dataset || {};

Y.Media.boba_lightbox_module_whitelist = Y.Media.boba_lightbox_module_whitelist || {};


Y.Media.boba_lightbox_module_targets['lightbox7b074328ba80f0e906939c94408a9450'] = {"lightboxId":"5beaad150e48e74b27ba30e31680d570","pivotId":"8c9c5d48-1003-38e5-8cba-ae9828acbda7"};


Y.Media.boba_lightbox_module_dataset['5beaad150e48e74b27ba30e31680d570'] = {"spaceid":"1197280665","total":1,"photoby":"Photo By","xhrtype":"slideshow","videoconf":{"autoplay":true,"continuousPlay":true,"mute":false,"volume":"1.00","lang":"en-US","site":"news","region":"US","jurisdiction":"US","YVAP":{"accountId":"145","playContext":"default"},"pageSpaceId":"1197280665","comscoreC4":"US News","comscoreC6":"","showEmbedCode":true,"showShareUrl":true,"expName":"MediaArticleRelatedLightbox","expType":"inline","apiEnv":"prod"},"slideshow_id":null,"slideshow_title":null,"slideshow_title_baked_html":null,"slideshow_desc":null,"slideshow_rev":null,"slideshow_plink_vita":null,"photos":[{"type":"image","url":"http:\/\/l3.yimg.com\/bt\/api\/res\/1.2\/V9xx2l9jTi4JXe9pC3c9TQ--\/YXBwaWQ9eW5ld3M7Zmk9aW5zZXQ7aD0zMDA7cT03OTt3PTQ1MA--\/http:\/\/media.zenfs.com\/en_us\/News\/Reuters\/2012-11-02T201400Z_1_CBRE8A11JVJ00_RTROPTP_2_GOOGLE.JPG","width":450,"height":300,"uuid":"8c9c5d48-1003-38e5-8cba-ae9828acbda7","caption":"Attendees gather at the Android developer sandbox during the Google I\/O Conference at Moscone Center in San Francisco, California June 28, 2012. REUTERS\/Stephen Lam","captionBakedHtml":"

Attendees gather at the Android developer sandbox during the Google I\/O Conference at Moscone Center in San Francisco, California June 28, 2012. REUTERS\/Stephen Lam","date":"Fri, Nov 2, 2012 4:16 PM EDT","credit":"Reuters","byline":"\ufffd Stephen Lam \/ Reuters","provider":"Reuters","photo_title":"Attendees gather at the Android developer sandbox during the Google I\/O Conference in San Francisco","pivot_alias_id":"attendees-gather-android-developer-sandbox-during-google-o-photo-200645766","plink":"\/photos\/attendees-gather-android-developer-sandbox-during-google-o-photo-200645766.html","plink_vita":"http:\/\/news.yahoo.com\/photos\/attendees-gather-android-developer-sandbox-during-google-o-photo-200645766.html","srchtrm":"Attendees gather at the Android developer sandbox during the Google I\/O Conference in San Francisco","revsp":"","rev":"21e4e7c0-252a-11e2-a7d5-a4e5802e1c8f","surl":"http:\/\/l.yimg.com\/bt\/api\/res\/1.2\/aXNb.Hjk6iN0EEJTYGBVkg--\/YXBwaWQ9eW5ld3M7Zmk9aW5zZXQ7aD01NjtxPTc5O3c9ODQ-\/http:\/\/media.zenfs.com\/en_us\/News\/Reuters\/2012-11-02T201400Z_1_CBRE8A11JVJ00_RTROPTP_2_GOOGLE.JPG","swidth":84,"sheight":56}]};

Y.Media.boba_lightbox_module_configs['5beaad150e48e74b27ba30e31680d570'] = {"spaceid":"1197280665","ult_pt":"story-lightbox","darla_id":"","images_total":0,"xhr_url":"\/_xhr\/related-article\/lightbox\/?id=048ccb9d-45dd-354e-b2f5-74c9b098ca33","xhr_count":20,"autoplay_if_first_item_is_video":true};
});
Y.later(10, this, function() {new Y.Media.RelatedArticle({count:"2",start:"1",
mod_total:"10", total:"0",
content_id:"048ccb9d-45dd-354e-b2f5-74c9b098ca33",
spaceid:"1197280665",
related_count:"-1"
});
});
Y.later(10, this, function() {(function(d){
d.getElementsByTagName('head')[0].appendChild(d.createElement('script')).src='http://d.yimg.com/oq/js/csc_news-en-US-core.js';
})(document);
});
Y.later(10, this, function() {
if(!("Media" in YAHOO)){YAHOO.Media = {};}
if(!("ugcrate" in YAHOO.Media)){YAHOO.Media.ugcrate = {};}
if(!("Media" in Y)){Y.namespace("Media");}
YAHOO.Media.ugcrate.ratings_fd3182a74fc12b41f9c3ecb0597e49b1 = new Y.Media.UgcRate({"context_id":"1b05b3fc-d288-43a3-bf0f-c88b56b4f5a8","sCrumb":"","containerId":"yom-sentimentrate-fd3182a74fc12b41f9c3ecb0597e49b1","rateDimensions":"d1","appLang":"en-US","sUltSId":"1197280665","sUltProperty":"news-en-US","sUltCampaign":"","sUltPlatform":"ugcwidgets","sUltIntl":"US","sUltLang":"en-US","selfPageUrl":"http:\/\/news.yahoo.com\/googles-android-software-3-4-smartphones-200645049--sector.html?_esi=0","artContentId":"048ccb9d-45dd-354e-b2f5-74c9b098ca33","sUltQstnTxt":"What do you think of the iPad Mini?","artContentTitle":"Google\\'s Android software in 3 out of 4 smartphones","artContentDesc":"SAN FRANCISCO (Reuters) - Three out of every four smartphones sold in the third quarter featured Google Inc\\'s Android mobile operating system, as the gap between Google and Apple Inc-based phones widened further, according to a new research report. Shipments of Android-based smartphones made by Samsung, HTC and other vendors nearly doubled in the third quarter, reaching 136 million units, according to industry research firm IDC. The strong sales boosted Android\\'s share of the worldwide smartphone market to 75 percent, from 57.5 percent in the year-ago period. ...","sUltBucketId":"test1","sUltSection":"sentirating","sUltBeaconUrl":"","sUltRecordPageviews":"1","sUltBeaconEnable":"1","serviceUrl":"\/_xhr","publisherContextId":"","propertyId":"2fcd79b5-b3a3-333e-b98e-722536a6698f","configurationId":"435db9ee-c55e-3766-b20d-c8ad3ff889d1","graphId":"","labelLeft":"Yawn..","labelRight":"I need to have it!","labelMiddle":"","itemimg":"http:\/\/l.yimg.com\/a\/i\/ww\/met\/yahoo_logo_us_061509.png","selfURI":"","aggregateRatingCount":"7078","aggregateReviewCount":"0","leftBlocksNum":"6166","rightBlocksNum":"910","leftBlocksPerCent":"87","rightBlocksPerCent":"13","ugcrate_apihost":"api01-us.ugcl.yahoo.com:4080","publisher_id":"news-en-US","yca_cert":"yahoo.ugccloud.app.trusted_proxies","timeout_write":"5000","through_proxy":"false","optionStats":"{\"s1\":4871,\"s2\":370,\"s3\":287,\"s4\":338,\"s5\":300,\"s6\":910,\"s7\":0,\"s8\":0,\"s9\":0,\"s10\":0}","l10N":"{\"FIRST_TO_READ\":\"You are first to read this. Share your feelings and start a conversation.\",\"SHARE_YOUR_FEELINGS\":\"You too can share your feelings and start a conversation!\",\"HOW_YOUR_FRIENDS_THINK\":\"Share your response with your friends on Facebook\",\"PRE_SHARE_MSG\":\"Your Facebook friends on Yahoo! can see how you responded. To share your response on Facebook, click on the Facebook share option.\",\"START_THE_CONVERSATION\":\"Share\",\"THANKS_FOR_SHARING\":\"Your response has been shared with your friends on Facebook\",\"POLL_HEADER\":\"SOCIAL SENTIMENT\",\"SERVER_ERROR\":\"Oops there seems to be some error, please try again later\",\"LOADING\":\"Loading...\",\"SHARE_AFTER_COMMENT\":\"Your response has been shared on Facebook.\",\"UNDO\":\"Undo\",\"UNIT_PEOPLE\":\"People\",\"NUM_PEOPLE_DISAGREE\":\"disagree with your opinion.\",\"READ_MORE_TEXT\":\"Read what they have to say.\",\"SLIDER_THUMB_WORDING_BEFORE_VOTING\":\"WHAT DO YOU THINK?\",\"SLIDER_THUMB_WORDING_VERB_BEFORE_VOTING\":\"DRAG\",\"SLIDER_THUMB_WORDING_THANKS_VOTING\":\"Thanks for voting\",\"NUM_PEOPLE_ANSWERED\":\" 7,078 people have responded\",\"ONE_PERSON_ANSWERED\":\" 1 person has responded. Your response will be seen by your Facebook friends on Yahoo!\",\"TWO_PEOPLE_ANSWERED\":\" 2 people have responded. Your response will be seen by your Facebook friends on Yahoo!\",\"NUM_PEOPLE_ANSWERED_AND_SHARED\":\" 7,078 people have responded. Your response will be seen by your Facebook friends on Yahoo!\",\"NUM_PEOPLE_RATED__s1\":4871,\"NUM_PEOPLE_RATED__s2\":370,\"NUM_PEOPLE_RATED__s3\":287,\"NUM_PEOPLE_RATED__s4\":338,\"NUM_PEOPLE_RATED__s5\":300,\"NUM_PEOPLE_RATED__s6\":910,\"NUM_PEOPLE_RATED__s7\":0,\"NUM_PEOPLE_RATED__s8\":0,\"NUM_PEOPLE_RATED__s9\":0,\"NUM_PEOPLE_RATED__s10\":0}","fbconfig":"{\"message\":\"undefined\",\"name\":\"undefined\",\"link\":\"\",\"source\":\"\",\"picture\":\"http:\\\/\\\/l.yimg.com\\\/a\\\/i\\\/ww\\\/news\\\/2011\\\/09\\\/27\\\/yahoo-tc.jpg\",\"description\":\"\",\"captionLeft\":\"undefined\",\"captionRight\":\"undefined\",\"app_id\":\"196660913708276\",\"redirect_uri\":\"\\\/_xhr\\\/ugcratefbredirect\\\/\"}","template_id":"LONG_SLIDER_SOUTH","obj_id":"ratings_fd3182a74fc12b41f9c3ecb0597e49b1","opt_count":"6","opt_color1":"","opt_color2":"","template_html":"
Read More..

How Computational Models Are Improving Medicine [Video]

























Click here to view the video


High-resolution electromechanical model of a heart; courtesy of N. Trayanova




















The more we learn about cancer, heart disease and Alzheimer’s, the more vexingly complex they seem–and the more elusive their cures. Even with cutting-edge imaging technology, biomarker tests and genetic data, we are still far from understanding the multifaceted causes and varied developmental stages of these illnesses. With the advent of powerful computing, better modeling programs and a flood of raw biomedical data, researchers have been anticipating a leap forward in their abilities to decipher the intricate dynamics involved human disease. Now, these computational capabilities are starting to arrive, according to a new analysis published online this week in Science Translational Medicine. In fact, “the field has exploded,” Raymond Winslow, director of the Johns Hopkins Institute for Computational Medicine, and co-author of the review, said in a prepared statement. Medicine and medical research largely have been focused on small specialties and narrow studies. But the body is a whole system–not isolated organ groups–and it is in constant interaction with the wider environment, including pollutants, toxins and other stressors. The resulting interactions do not only work in a single direction; instead, we have learned that there are feed-forward and feedback loops and crosstalk on cellular, molecular and genetic levels. This nexus is where advances in computational medicine are poised to make a large contribution. “Computational medicine can help you see how the pieces of the puzzle fit together to give a more holistic picture,” Winslow said. “We may never have all of the missing pieces, but will wind up with a much clearer view of what causes disease and how to treat it.” Models comparing gene expression in different patients have already successfully helped to determine different grades of prostate cancer, predict how different patients will respond to breast cancer treatment and find different types of stomach cancer. Scientists are also taking advantage of more advanced anatomical data to model whole organs and their function–and dysfunction. Using, for example, diffusion tensor magnetic resonance imaging, researchers can collect detailed information about heart anatomy, fiber and structure. This macro structure can be combined with more cellular-based models for “unprecedented structural and biophysical detail, including cardiac electromechanics,” the researchers noted in their paper. With this information, scientists are learning more about blood-flow dynamics, arrhythmia and heart attacks. These new models are now starting to be translated back to individual patients, to help find better treatments. Computational-medicine algorithms from detailed brain maps have already been used to develop an iPad app that is being used clinically to help doctors decide on deep brain stimulation locations and strengths. These models, however, also need to be checked frequently against real-world data and adjusted accordingly. But researchers who are armed to deal with this once unusual cross-discipline endeavor are growing more common. “There is a whole new community of people being trained in mathematics, computer science and engineering, and they are being cross-trained in biology,” Winslow said. “This allows them to bring a whole new perspective to medical diagnosis and treatment.” The myriad applications for computational medicine approaches are only beginning to be explored, the researchers noted. “As we gain confidence in the ability of computational models to predict human biological processes, they will help guide us through the complex landscape of disease, ultimately leading to more effective and reliable methods for disease diagnosis, risk stratification and therapy,” the researchers wrote. “We are poised at an exciting moment in medicine.”

Video of electromechanical heart model courtesy of N. Trayanova


Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.


Health News Headlines – Yahoo! News



Read More..

With three days to go, Romney calls his campaign a ‘movement’

Republican presidential candidate Mitt Romney (Jim Young/Reuters)PORTSMOUTH, N.H.—Mitt Romney kicked off a whirlwind weekend of campaigning across the country in the state where he launched his bid for the presidency, expressing confidence that he will win the election.


"New Hampshire won me the Republican nomination, and New Hampshire is going to get me to the White House," the Republican nominee said at the first of four scheduled rallies on Saturday.


Speaking to more than 1,000 voters here at a chilly airport rally, Romney sounded a more retrospective note heading into the final weekend of the campaign.


"I've watched over the last few months as our campaign has gone from a start to a movement. It's not just the size of the crowds. It's the conviction and compassion in the hearts of the people," Romney said. "It's made me strive to be more worthy of the support I have received across the country and to campaign as I would govern, to speak for the aspirations of all Americans, not just some Americans."


From here, Romney will travel to Dubuque, Iowa, and then to Colorado, where he will hold rallies in Colorado Springs and Englewood. He'll spend the night in Des Moines, where he's scheduled to hold a rally Sunday morning.


Saturday's rally was Romney's first appearance in this hotly contested swing state in more than a month. Romney launched his campaign in the state in June 2011 and will hold his final rally here on Monday night in Manchester. Recent polls have found the GOP nominee statistically tied with President Barack Obama heading into Election Day.


Read More..

Syria army quits base on strategic Aleppo road

























BEIRUT (Reuters) – The Syrian army abandoned its last base near the northern town of Saraqeb after a fierce assault by rebels, further isolating the strategically important second city Aleppo from the capital.


But in a political setback to forces battling to topple President Bashar al-Assad, the United Nations said the rebels appeared to have committed a war crime after seizing the base.





















The opposition Syrian Observatory for Human Rights said on Friday government troops had retreated from a post northwest of Saraqeb, leaving the town and surrounding areas “completely outside the control of regime forces”.


It was not immediately possible to verify the reported army withdrawal. Authorities restrict journalists’ access in Syria and state media made no reference to Saraqeb.


The pullout followed coordinated rebel attacks on Thursday against three military posts around Saraqeb, 50 km (30 miles) southwest of Aleppo, in which 28 soldiers were killed.


Several were shown in video footage being shot after they had surrendered.


“The allegations are that these were soldiers who were no longer combatants. And therefore, at this point it looks very likely that this is a war crime, another one,” U.N. human rights spokesman Rupert Colville said in Geneva.


“Unfortunately this could be just the latest in a string of documented summary executions by opposition factions as well as by government forces and groups affiliated with them, such as the shabbiha (pro-government militia),” he said.


Video footage of the killings showed rebels berating the captured men, calling them “Assad’s dogs”, before firing round after round into their bodies as they lay on the ground.


Rights groups and the United Nations say rebels and forces loyal to President Bashar al-Assad have committed war crimes during the 19-month-old conflict. It began with protests against Assad and has spiraled into a civil war which has killed 32,000 people and threatens to drag in regional powers.


The mainly Sunni Muslim rebels are supported by Sunni states including Saudi Arabia, Qatar and neighboring Turkey. Shi’ite Iran remains the strongest regional supporter of Assad, who is from the Alawite faith which is an offshoot of Shi’ite Islam.


STRATEGIC BLOW


Saraqeb lies at the meeting point of Syria’s main north-south highway, linking Aleppo with Damascus, and another road connecting Aleppo to the Mediterranean port of Latakia.


With areas of rural Aleppo and border crossings to Turkey already under rebel control, the loss of Saraqeb would leave Aleppo city further cut off from Assad’s Damascus powerbase.


Any convoys using the highways from Damascus or the Mediterranean city of Latakia would be vulnerable to rebel attack. This would force the army to use smaller rural roads or send supplies on a dangerous route from Al-Raqqa in the east, according to the Observatory’s director, Rami Abdelrahman.


In response to the rebels’ territorial gains, Assad has stepped up air strikes against opposition strongholds, launching some of the heaviest raids so far against working class suburbs east of Damascus over the last week.


The bloodshed has continued unabated despite an attempted ceasefire, proposed by join U.N.-Arab League envoy Lakhdar Brahimi to mark last month’s Muslim holiday of Eid al-Adha.


In the latest in a string of fruitless international initiatives, China called on Thursday for a phased, region-by-region ceasefire and the setting up of a transitional governing body – an idea which opposition leaders hope to flesh out at a meeting in Qatar next week.


Veteran opposition leader Riad Seif has proposed a structure bringing together the rebel Free Syrian Army, regional military councils and other rebel forces alongside local civilian bodies and prominent opposition figures.


His plan, called the Syrian National Initiative, calls for four bodies to be established: the Initiative Body, including political groups, local councils, national figures and rebel forces; a Supreme Military Council; a Judicial Committee and a transitional government made up of technocrats.


The initiative has the support of Washington. U.S. Secretary of State Hillary Clinton called on Wednesday for an overhaul of the opposition, saying it was time to move beyond the troubled Syrian National Council.


The SNC has failed to win recognition as the legitimate representative of the Syrian people and Clinton said it was time to bring in “those on the front lines fighting and dying”.


(Additional reporting by Oliver Holmes in Beirut and Stephanie Nebehay in Geneva; Editing by Jon Boyle)


World News Headlines – Yahoo! News



Read More..

AP PHOTOS: Stars come out for Sandy victims’ show

























NEW YORK (AP) — For the victims of Superstorm Sandy, it was a sorely needed message delivered.


From “Livin’ on a Prayer” to “The Living Proof,” every song Friday at NBC’s benefit concert became a message song.





















New Jersey‘s Jon Bon Jovi gave extra meaning to “Who Says You Can’t Go Home.” Billy Joel worked in a reference to Staten Island, the decimated New York City borough.


The hourlong event, hosted by Matt Lauer, was heavy on stars and lyrics identified with New Jersey and the New York metropolitan area, which took the brunt of this week’s deadly storm. The telethon was a mix of music, storm footage and calls for donations from Jon Stewart, Tina Fey, Whoopi Goldberg and others.


The show ended, as it only could, with Bruce Springsteen and the E Street Band, tearing into “Land Of Hope and Dreams.”


“God bless New York,” Springsteen, New Jersey‘s ageless native son, said in conclusion. “God bless the Jersey shore.”


Here, in pictures, are some of the performers on this somber but hopeful night:


Entertainment News Headlines – Yahoo! News



Read More..

Microsoft vs Google trial raises concerns over secrecy

SAN FRANCISCO (Reuters) - Two weeks before a high-stakes trial pitting Google's Motorola Mobility unit against Microsoft, Google made what has become a common request for a technology company fighting for billions of dollars: A public court proceeding, conducted largely in secret.


Google and Microsoft, like rivals embroiled in smartphone patent wars, are eager to keep sensitive business information under wraps - in this case, the royalty deals they cut with other companies on patented technology. Microsoft asked for similar protections in a court filing late on Thursday.


Such royalty rates, though, are the central issue in this trial, which begins November 13 in Seattle.


U.S. District Judge James Robart has granted requests to block many pre-trial legal briefs from public view. Though he warned he may get tougher on the issue, the nature of the case raises the possibility that even his final decision might include redacted, or blacked-out, sections.


Legal experts are increasingly troubled by the level of secrecy that has become commonplace in intellectual property cases where overburdened judges often pay scant attention to the issue.


Widespread sealing of documents infringes on the basic American legal principle that court should be public, says law professor, Dennis Crouch, and encourages companies to use a costly, tax-payer funded resource to resolve their disputes.


"There are plenty of cases that have settled because one party didn't want their information public," said Crouch, an intellectual property professor at University of Missouri School of Law.


Tech companies counter that they should not be forced to reveal private business information as the price for having their day in court.


The law does permit confidential information to be kept from public view in some circumstances, though companies must show the disclosure would be harmful.


Google argues that revelations about licensing negotiations would give competitors "additional leverage and bargaining power and would lead to an unfair advantage."


Robart has not yet ruled on Google and Microsoft's requests, which, in the case of Google includes not only keeping documents under seal, but also clearing the courtroom during crucial testimony.


It is also unclear whether Robart will redact any discussion of royalty rates in his final opinion. The judge, who will decide this part of the case without a jury, did not respond to requests for comment.


NOT PAYING ATTENTION


Apple Inc and Microsoft Corp have been litigating in courts around the world against Google Inc and partners like Samsung Electronics Co Ltd, which use the Android operating system on their mobile devices.


Apple contends that Android is basically a copy of its iOS smartphone software, and Microsoft holds patents that it contends cover a number of Android features.


Google bought Motorola for $12.5 billion, partly to use its large portfolio of communications patents as a bargaining chip against its competitors.


Robart will decide how big a royalty Motorola deserves from Microsoft for a license on some Motorola wireless and video patents.


Apple, for its part, is set to square off against Motorola on Monday in Madison, Wisconsin, in a case that involves many of the same issues.


In Wisconsin, Apple and Motorola have filed most court documents entirely under seal. U.S. District Judge Barbara Crabb did not require them to seek advance permission to file them secretly, nor did she mandate that the companies make redacted copies available for the public.


Judges have broad discretion in granting requests to seal documents. The legal standard for such requests can be high, but in cases where both sides want the proceedings to be secret, judges have little incentive to thoroughly review secrecy requests.


In Apple's Northern California litigation against Samsung, both parties also sought to keep many documents under seal. After Reuters challenged those secrecy requests, on grounds it wanted to report financial details, U.S. District Judge Lucy Koh ordered both companies to disclose a range of information they considered secret - including profit margins on individual products - but not licensing deals. Apple and Samsung are appealing the disclosure order.


In response to questions from Reuters last week, Judge Crabb in Wisconsin, who will also decide the case without a jury, acknowledged she had not been paying attention to how many documents were being filed under seal. Federal judges in Madison will now require that parties file redacted briefs, she said, though as of Wednesday, Apple and Motorola were still filing key briefs entirely under seal.


"Just because there is a seed or kernel of confidential information doesn't mean an entire 25-page brief should be sealed," said Bernard Chao, an intellectual property professor at University of Denver Sturm College of Law.


Crabb promised that the upcoming trial would be open.


"Whatever opinion I make is not going to be redacted," she told Reuters in an interview.


CHECKING THE COMPS


Microsoft sued Motorola two years ago, saying Motorola had promised to license its so-called "standards essential" patents at a fair rate, in exchange for the technology being adopted as a norm industrywide. But by demanding roughly $4 billion a year in revenue, Microsoft says Motorola broke its promise.


Robart will sort out what a reasonable royalty for those standards patents should be, partly by reviewing deals Motorola struck with other companies such as IBM and Research in Motion - much like an appraiser checking comparable properties to figure out whether a home is priced right.


In this case, though, the public may not be able to understand exactly what figures Robart is comparing. Representatives for Microsoft and Google declined to comment.


In its brief, Microsoft said licensing terms could be sealed without the need to clear the courtroom.


"Permitting redaction of this information will minimize the harm to Microsoft and third parties while also giving due consideration to the public policies favoring disclosure," the company argued.


IBM and RIM have also asked Robart to keep licensing information secret.


Chao doesn't think Robart will ultimately redact his own ruling, even though it may include discussion of the specific royalty rates. "I can't imagine that," he said.


Most judges cite lack of resources and overflowing dockets as the reason why they don't scrutinize secrecy requests more closely, especially when both parties support them.


In Wisconsin, Crabb said that even though she will now require litigants to ask permission to file secret documents, it is highly unlikely that she will actually read those arguments - unless someone else flags a problem.


"We're paddling madly to stay afloat," Crabb said.


The Wisconsin case in U.S. District Court, Western District of Wisconsin is Apple Inc. vs. Motorola Mobility Inc., 11-cv-178. The Seattle case in U.S. District Court, Western District of Washington is Microsoft Corp. vs. Motorola Inc., 10-cv-1823.


(Reporting by Dan Levine in San Francisco; Additional reporting by Bill Rigby in Seattle.; Editing by Jonathan Weber, Andrew Hay and Bernadette Baum)


Read More..